Testosterone Therapy and Female Orgasm
that “clinical trials have shown that exogenous testosterone therapy
improves female arousability, sexual desire and fantasy, frequency of sexual
activity and orgasm, and satisfaction and pleasure from the sexual act.”
Testosterone therapy in women: its role in the management of hypoactive
sexual desire disorder.
R.T. Abdallah, J.A.
Simon,Department of Obsterics and Gynecology, George Washington University,
Washington, DC 20036, USA,
Int J Impot Res. 2007 Sep-Oct;19(5):458-63. Epub 2007 Jun 21.
Disorders of sexual dysfunction
occur in nearly half of women during their life, and hypoactive sexual
desire disorder accounts for most of those complaints. Although the
relationship between low endogenous testosterone levels and sexual desire
disorders in women has not been empirically established, clinical trials
have shown that exogenous testosterone therapy improves arousability, sexual
desire and fantasy, frequency of sexual activity and orgasm, and
satisfaction and pleasure from the sexual act. Its therapeutic role in bone
mineral density, fatigue, well-being and hot flashes requires more study
before specific recommendations can be made. Potential adverse effects of
testosterone therapy include hirsutism, acne and deepening of the voice
along with changes in lipid profiles. While less well understood, concern
after increased risks for breast cancer and cardiovascular events has been
raised about this therapy. Testosterone therapy is available in various
formulations; the most commonly used are oral and transdermal, including
patches, gels, creams and ointments.
PMID: 17581596 [PubMed - indexed